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See Santa María la Mayor, Argentina (UNESCO site)

Reducción de Santa María la Mayor (Reduction of Holy Maria Major), located in the Santa María Department of the Misiones Province, Argentina, was one of the missions or reductions founded in the 17th century by the Jesuits in the Americas during the Spanish colonial period. The ruins of the reduction were declared World Heritage Site by UNESCO in 1984, together with other reductions in the area. The ruins have been taken over by vegetation, and are not as well preserved as those of San Ignacio Miní, also in Misiones. The Jesuit reduction was found in founded in 1626, and by 1744 it held a population of 993. It was abandoned when the Jesuits were expelled from the Spanish colonies in 1767.
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